Bateson-Dobzhansky-Muller model

The Bateson-Dobzhansky-Muller model describes how genetic incompatibility can evolve between populations that have become separated from one another. As isolated populations accumulate different mutations, each mutation may be harmless or even beneficial within its own population, but when the two populations later interbreed, these independently evolved genes can interact for the first time and produce incompatibilities that lower the fitness of the hybrid offspring. The model was first proposed by William Bateson in 1909 and later developed further by Theodosius Dobzhansky and Herman Muller, and it remains a standard explanation for how reproductive isolation, and so speciation, can build up gradually. This description is adapted from Wikipedia contributors under CC BY-SA 4.0; changes were made. https://creativecommons.org/licenses/by-sa/4.0/