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Epstein-Barr virus

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The Epstein-Barr virus, also known as human herpesvirus 4, is one of the nine known human herpesvirus types and one of the most common viruses in humans. It is a double-stranded DNA virus and was the first virus identified as directly oncogenic, meaning it can cause cancer. The virus establishes a permanent infection in human B cells and is the most common cause of infectious mononucleosis, and it is also tightly linked to several malignant diseases. Various vaccine formulations have been tested in humans and other animals, but none has prevented infection and no vaccine has been approved.

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